Antabuse (Disulfiram) Treatment for Alcohol Use Disorder

Disulfiram, also known as Antabuse, is a medication used to treat alcohol use disorder (AUD) and alcoholism. It interferes with the metabolism of alcohol by binding to aldehyde dehydrogenase (ALDH), a liver enzyme. It acts as a deterrent to those who wish to drink alcohol but may not be able to stop it due to its adverse effects.

In this article, we will explore the use of Antabuse and its efficacy in helping people stop drinking. However, this medicine is effective according to the doctor’s advice. One of the best alcohol addiction drug rehab centers in the United States that provide you with effective medication-assisted treatment programs to overcome substance abuse is The Recovery Team.

Key Takeaways

Antabuse (Disulfiram) is a medication used to treat alcohol use disorder.

  • Antabuse works by interfering with the body’s ability to process alcohol. This can lead to unpleasant reactions, such as nausea, vomiting, and diarrhea.
  • Antabuse is usually taken once a day. Patients should not take it with other medications that contain sulfa (such as antibiotics) because they can increase the chances of severe side effects.
  • It is essential to be aware of the side effects when taking the medication.
  • Antabuse is most effective when combined with counseling and other treatment programs for alcohol use disorder.

Get effective treatment programs and counseling services from one of the renowned rehab centers in Florida, The Recovery Team. Call us now at (800) 817-1247.

What is Antabuse (Disulfiram)?

Brand name Antabuse (Disulfiram) is a drug that is used to treat people who have alcohol dependence. It works by stopping the person from drinking alcohol. Antabuse can cause serious side effects if taken by someone who is also pregnant.

Antabuse and Disulfiram prescription medication does not reduce alcohol withdrawal symptoms but can help reduce the amount of alcohol.

The History of Disulfiram

Disulfiram, also known as Antabuse, was first developed in the early 1900s as an anti-alcohol drug. It is a medication used to treat alcoholism and effectively reduces alcohol consumption.

Disulfiram works by causing unpleasant reactions when alcohol is consumed, leading to an increased desire to avoid alcohol. Disulfiram was initially used as an anti-alcohol drug, but it has since been used more broadly in treating alcoholism.

The medication works by causing unpleasant reactions when alcohol is consumed, leading to an increased desire to avoid alcohol. Disulfiram effectively reduces alcohol consumption and has been approved by the FDA to treat alcoholism.

Use of Disulfiram

Antabuse (Disulfiram) is one drug that has been used for more than 50 years to treat alcohol use disorder. Antabuse can lessen a person’s urge to drink through nausea it causes and can help reduce drinking during a relapse. Set yourself up for success by understanding how Antabuse works and what to expect when taking it.

Recommended Doses of Disulfiram

Disulfiram works by reducing the amount of alcohol that people drink. The recommended doses of Disulfiram depend on how severe the person’s alcoholism is.

Usually, doctors prescribe the recommended doses of Disulfiram are 200 mg and 300 mg, taken in two divided doses. But it is essential to get medical advice and tell your medical history before taking Disulfiram.

It can be a deterrent as it causes unpleasant side effects and makes people feel sick when they drink alcohol. Disulfiram is not recommended for use by people who have liver problems. It can also cause serious side effects, including seizures, heart attacks, chest pain, kidney disease, respiratory depression, and death.

How Does Antabuse Works?

Antabuse is a medication that works to prevent alcohol abuse. It blocks the action of alcohol in the body, causing a person who takes it to experience unpleasant symptoms if they drink.

These symptoms can include an uncomfortable burning sensation in the throat and stomach, increased heart rate, nausea, vomiting, and sweating.

Antabuse is most commonly used to treat people with alcohol use disorder who cannot stop drinking without it. It can also be used in people with occasional or moderate drinking problems.

It is a type of drug called an anticonvulsant. Antabuse works by making people sick if they drink alcohol. It causes nausea, vomiting, and diarrhea. This can make it difficult for people to drink alcohol and stay drunk.

How Should You Take Antabuse?

Antabuse is a medication that helps people addicted to alcohol quit drinking. It makes people feel very sick, often causing vomiting, diarrhea, and trouble breathing. It’s crucial to take Antabuse correctly to ensure it works best.

To take Antabuse, you need to be admitted to a hospital or treatment center where they will give you the medication. You must also abstain from drinking for 8 hours before taking the medication and for 12 hours afterward. If you drink any alcohol during those 8 or 12 hours, the medication will not work, and you will have to start over.

It’s also essential to track how much you drink while taking Antabuse. If you drink more than the recommended amount within 24 hours of taking the medication, it can worsen your symptoms, and you may have to stop taking it.

Steps you Need to Follow While Taking Antabuse

If you are taking Antabuse for alcoholism, the instructions below will outline how to take the medication. If you are taking Antabuse for other reasons, such as to prevent a false positive drug test, the instructions below may vary. To take Antabuse orally, follow these steps:

1) Drink plenty of fluids before taking Antabuse. This will help offset any nausea that may occur.

2) Swallow Antabuse tablets whole with a full glass of water. Do not crush or chew the tablets. Doing so can lead to negative effects on the medication’s effectiveness.

3) Wait at least two hours after eating before taking Antabuse. This will give the medication time to work its way through your system.

4) Follow up with a doctor if you experience any adverse side effects from Antabuse, such as stomach pain, drowsiness, difficulty breathing, or seizures.

When Should You Not Take Antabuse (Disulfiram)?

Antabuse (Disulfiram) is a medication that can help people who have an alcohol use disorder stop drinking. It works by making people feel sick when they drink alcohol.

People who take Antabuse should not drink alcohol if they have any of the following:

  • A heart condition.
  • A history of seizures or blackouts caused by drinking alcohol.
  • A liver problem that causes jaundice (yellowing of the skin and eyes) or liver failure.
  • Pregnant or trying to get pregnant.
  • A mental health problem, such as depression, makes it challenging to control drinking.

Side Effects of Antabuse

Antabuse (Disulfiram) works by preventing people from drinking alcohol and experiencing the harmful side effects of drinking. Side effects of Antabuse can include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Rash
  • Dizziness
  • Confusion

Disulfiram-Alcohol Reaction

Disulfiram-alcohol reaction is a well-known complication during alcohol detoxification. Disulfiram induces flushing, sweating, and feelings of anxiety and intoxication. Alcohol can further worsen Disulfiram’s effects, leading to a potentially fatal interaction.

The main culprit in disulfiram-alcohol reactions is ethanol. Ethanol increases the levels of Disulfiram in the blood, which can cause dizziness, confusion, and even seizures. In extreme cases, ethanol can also lead to liver damage and death.

To avoid disulfiram-alcohol reactions, it is important to monitor one’s symptoms closely while detoxing and to avoid drinking alcohol while taking the drug. Individuals who experience disulfiram-alcohol reactions should also seek medical attention as soon as possible.

Effects of Drinking While on Antabuse

When taking Antabuse to prevent drinking, they are typically advised not to drink. Drinking while on Antabuse can have several adverse effects, including drowsiness, dizziness, blurred vision, and rapid heart rate. In extreme cases, drinking while on Antabuse can lead to seizures and even death.

Alcoholism is a chronic, relapsing problem that can hurt many aspects of an individual’s life. One of the most common consequences of alcoholism is alcohol-related problems such as liver damage, falls, car accidents, and domestic violence.

One of the significant ways that drinking can cause problems is by altering how the body processes drugs like Antabuse. Antabuse is a medication used to help people trying to quit drinking alcohol.

When taken in combination with alcohol, Antabuse causes intense feelings of anxiety and nausea. These symptoms can last for up to 12 hours after drinking alcohol and can prevent people from drinking again.

There are a few ways that drinking while taking Antabuse can affect an individual’s health:

Liver Damage

The liver breaks down alcohol into molecules the body can use. When alcohol consumption exceeds the body’s ability to process it, it can damage the liver. This damage may lead to cirrhosis (a severe liver disease), liver failure, or death.


Drinking while on Antabuse increases your chances of falling because it makes you feel dizzy and lightheaded. This condition is an anticholinergic syndrome and can lead to falls and injuries.

Car Accidents

Drinking while on Antabuse increases your chances of getting in a car accident because it makes you feel drunk and careless. Alcohol impairs your judgment and ability to drive safely, which could cause road accidents.

Antabuse Interactions with Other Drugs

When Antabuse is taken with other drugs, the effects of each drug can vary. For example, when Antabuse is taken with alcohol, it can increase the effects of both substances. When Antabuse is taken with other depressants, such as benzodiazepines, the depressant effects of the other drug may be increased.

Antabuse is a medication used to help people quit alcohol. It can also cause other drug interactions. One potential interaction between Antabuse and other medications is that Antabuse can increase the effects of certain drugs.

This is especially true if the other drug is a depressant, like barbiturates or benzodiazepines. Antabuse can also increase the effects of stimulants like cocaine or methamphetamine. If you are taking any medications, you must talk to your doctor about the safest combination.

Too much of one kind of medication can have dangerous side effects, while mixing different types of medications can lead to unexpected interactions.

How Long to Wait After Taking Disulfiram?

After taking Disulfiram, it can take up to two weeks for the full benefits of the medication to be realized. The first week is typically the most active, with increased motivation and energy. However, after that initial week, there may be a gradual decrease in these symptoms. It can take up to six weeks for Disulfiram to have its full effect, so it is essential to track how you feel during this time.