The Dangers of Mixing Dayquil with Alcohol

Here’s What We’ll Cover

You’re Not Alone – We're Here to Help

Call us today to get the support and guidance you deserve.

Here’s What We’ll Cover

Dayquil is an OTC drug used to treat symptoms of a cold and flu, including a runny nose and sore throat. This medication relieves symptoms without causing drowsiness or dizziness, unlike Nyquil. Designed for daytime use, Dayquil works as a nasal decongestant thanks to phenylephrine, while Nyquil is geared for nighttime relief with its sedative ingredient, doxylamine succinate. Dayquil combines acetaminophen (to ease pain and reduce fever), dextromethorphan (to calm coughs), and phenylephrine (to clear nasal passages), offering effective relief during the day.

While Dayquil provides fast-acting comfort, it’s important to remember that its active ingredients can remain in your system for about a full day or two after use, depending on individual factors like metabolism and dosage. This makes it essential to use responsibly, especially when considering potential interactions.

Unfortunately, some misuse over-the-counter medications without considering how they interact with other substances. It’s always advised to drink only water while taking Vicks Dayquil to help relieve pain and restlessness from flu and cold.

Dayquil’s active ingredients can have serious adverse effects when mixed with alcohol. Vicks warns consumers about the risk of severe liver damage if the medication is combined with alcoholic beverages. Such a combination can lead to organ damage, nausea, vomiting, elevated blood pressure, and even hallucinations. For individuals struggling with alcohol addiction or use disorders, Dayquil should be avoided entirely. Combining alcohol with cough syrups or other medications is dangerous for your health and can lead to serious complications. If you’re looking for alcohol rehab in Delray Beach, Florida, The Recovery Team offers compassionate care and medically supervised detox services tailored to meet your individual needs. Our Delray Beach facility provides a safe and structured environment to help you overcome addiction and begin the path toward lasting recovery.

Side Effects of Combining Dayquil and Alcohol

If people consume the prescribed dose of Dayquil combined with alcohol, they may experience dizziness, anxiety, and trouble sleeping. Prolonged or excessive drinking alongside Dayquil can also trigger withdrawal symptoms, particularly when the body becomes dependent on the combination. Acetaminophen, a primary ingredient in Dayquil, is known to cause liver damage—especially when combined with alcohol. For those in need of inpatient alcohol rehab in Massachusetts, our Newton location offers medically managed treatment programs designed to support safe detox and long-term healing.

  • Fever
  • Liver damage
  • Lack of concentration
  • Unusual bleeding
  • Headache
  • Dizziness
  • Fatigue

Risks of Combining Dayquil with Alcohol

Since Dayquil consists of ingredients that interact with alcohol and increases the dangers of convulsions, liver damage, irregular sleeping cycle, overdose, and dizziness. A single drink of alcohol stays in our system for about 2-3 hours, and Dayquil is active in our body for 4-6 hours. According to U.S. Food and Drug Administration, OTC cough and cold medications can result in overdosing. They have warned parents to be careful when they treat their children’s fever and cough by using these medications. If someone consumes alcoholic drinks, they should ensure that Dayquil is not active in their system.

Acetaminophen with Alcohol

Acetaminophen is a pain reliever and is effective in treating cold symptoms. Acetaminophen other than Dayquil is used in 600 medications in the USA. Although doctors prescribe it as an effective pain reliever, it can cause severe liver damage. Dayquil manufacturer Procter and Gamble warns that acetaminophen should not be consumed with alcohol. Acetaminophen overdose is the leading cause of acute liver failure in the United States. Its overdose is the second leading cause of liver failure. Mixing alcohol with acetaminophen can lead to adverse side effects such as joint swelling, bruising, unusual bleeding, pale skin, tiredness, and loss of appetite.

Risk of Liver Damage

When you consume too much acetaminophen or take it with alcohol, it can negatively impact your liver. When the liver processes acetaminophen, it breaks down the substances in the drug. Those substances are then excreted in our urine. However, the liver cannot efficiently process one substance called NAPQI. The liver produces glutathione to break down NAPQI, which prevents liver damage. However, alcohol reduces the production of glutathione which increases NAPQI. Harmful effects of NAPQI include acetaminophen overdose. Symptoms of liver damage include abdominal pain, vomiting, and jaundice.

Dextromethorphan with Alcohol

Dextromethorphan is a cough suppressant used in Dayquil known as DXM. It works by numbing the sore throat and relieves pain. It is not safe when mixed with alcohol. Side effects of dextromethorphan such as lightheadedness, headache, and nausea. Some people experience difficulty in understanding and judgment. Substance abuse is common among teenagers who use excessive drugs, resulting in substance use disorder. Consuming more than the prescribed dose of DXM can result in lethargy, loss of concentration, high blood pressure, and hallucination. Flu medications consist of DXM, and combining it with alcohol can cause respiratory problems and sedation.

Dextromethorphan Overdose

Teenagers and young adults may misuse flu medications like Dayquil, mixing them with alcohol or other substances to heighten effects. This risky behavior can lead to overdose, organ damage, and dangerous psychological side effects. Dextromethorphan mixed with alcohol, in particular, increases the likelihood of respiratory issues, confusion, and erratic behavior. If you’re located in Cape Cod, alcohol rehab in Cape Cod is available to help individuals overcome addiction in a safe and supportive environment.

Interaction with other Drugs

Be cautious about the medicines you are taking, whether they are OTC or prescribed ones. Interactions can occur between cold medications and drugs that you consume. Dayquil can interact with antidepressants because it contains dextromethorphan, resulting in serotonin syndrome.

Dayquil with Doxylamine

Doxylamine interacts with dextromethorphan and increases its side effects. A person may feel difficulty focusing on a particular task. They will experience confusion, headache, nausea, and difficulty in motor coordination. You should avoid activities that require concentration and alertness, such as driving a vehicle. That is why it is best to inform your doctor about the medications that you are consuming before taking other medications.

Dayquil with Albuterol

High doses of Dayquil taken with medications like Albuterol may heighten the risk of cardiovascular issues, including elevated heart rate and blood pressure. This can be especially dangerous for individuals already dealing with substance use. Our New Jersey alcohol rehab program offers comprehensive support, including medical detox, therapy, and aftercare planning, to guide you through every phase of recovery.

Dayquil with Nyquil

Dayquil and Nyquil are used for cold and flu relief and contain Acetaminophen and Dextromethorphan. Dayquil does not have sedative effects, but Nyquil is a sedative antihistamine that helps patients to sleep. Although they both are cold relievers, it is not safe to consume them together. Taking both substances together can result in liver damage due to increased acetaminophen in the liver. If you have liver disease, ask a doctor before taking Dayquil or Nyquil.

Dayquil with Dietary Supplements

Dietary supplements include vitamins, minerals, amino acids, and many more. Combining nutritional supplements with cold medications can have life-threatening effects. Vitamin C can interact with acetaminophen and other cold medications. The doctor recommends avoiding them. According to the National Institute on Drug Abuse, millions of American misuse prescribed medication.

Dayquil with Prozac

Prozac increases the effects of dextromethorphan on your body. You may experience shortness of breath, drowsiness, anxiety, increased heart rate, diarrhea, and confusion. If you experience any of these symptoms, then immediately contact a doctor. You should inform your doctor about any medications, including dietary supplements.

Read More Alcohol Articles